What is Nootropic Stacking?

You may have heard of nootropic stacking, but for many, the concept is new.   

Nootropic stacking describes the use of two or more neuro-enhancing or brain-supportive supplements to achieve combined benefits. Often, a nootropic product will have one key benefit, such as memory, focus, energy, or stress relief. By using multiple products, you can “stack” or maximize your targeted benefits for brain health and cognitive function.  

Customization is Key  

Stacking nootropics with other brain health supplements helps you achieve personalized benefits. What products you include in your stack depends on your goals. For example, if you are looking for focus and clarity during an exam, you may decide to include ingredients like caffeine, phosphatidylserine, and adaptogens in your stack. Others may choose to target long-term brain health by stacking brain-boosting botanicals like amla or purslane with DHA-rich fish oil.  

Adaptogen Elixir to combat stress: This dietary supplement is designed to support your ability to adapt to stress by combining kombucha from black tea leaves with adaptogen root extracts from astragalus, eleuthero, rhodiola, ashwagandha, and schisandra fruit. Studies have found that adaptogens reduce mental fatigue and enhance physical endurance by helping the body “adapt” to better resist the effects of both physical and psychological stress (1, 2). Different adaptogens work in a variety of ways to help normalize the body’s functions in response to stress helping to improve both physical and mental performance (3).  

Cleanse for Life® : It may be formulated to support your body’s natural detoxification process and protect against oxidative stress, but the B vitamins and choline in Cleanse for Life are beneficial beyond Cleanse Days. A study published in the American Journal of Clinical Nutrition found that individuals who consumed higher levels of B vitamins, specifically niacin and folate, had higher cognitive function than their peers and comparable cognitive function to people four to six years younger (7). Choline is a micronutrient found in many foods such as eggs, beans, and quinoa that is key in brain growth and development. It is a precursor in acetylcholine production, a neurotransmitter important for memory, mood, and other brain functions (8).  

The key to nootropic stacking is choosing complementary ingredients to support your most important goals. Isagenix products like Adaptogen Elixir, AMPED Power, IsaOmega , and Cleanse for Life pair perfectly with Nootropic Elixir .   

References  

Darbinyan V, Kteyan A, Panossian A, et al. Rhodiola rosea in stress induced fatigue–a double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty. Phytomedicine. 2000 Oct;7(5):365-71.   
Panossian A, Wikman G. Evidence-based efficacy of adaptogens in fatigue, and molecular mechanisms related to their stress-protective activity. Curr Clin Pharmacol. 2009 Sep;4(3):198-219.  
Provino, R. The role of adaptogens in stress management. Aust. J. Medical Herbal. 2010 Jan;22(2):41-49.   
Rae CD & Bröer S. Creatine as a booster for human brain function. How might it work? Neurochem Int. 2015 Aug 18. pii: S0197-0186(15)30038-3.  
Stonehouse W, Conlon CA, Podd J, et al D. DHA supplementation improved both memory and reaction time in healthy young adults: a randomized controlled trial. Am J Clin Nutr. 2013 May;97(5):1134-43.  
D’Ascoli TA, Mursu J, Voutilainen S, et al. Association between serum long-chain omega-3 polyunsaturated fatty acids and cognitive performance in elderly men and women: The Kuopio Ischaemic Heart Disease Risk Factor Study. Eur J Clin Nutr. 2016 Aug;70(8):970-5.
Qin B, Xun P, Jacobs DR Jr, et al. Intake of niacin, folate, vitamin B-6, and vitamin B-12 through young adulthood and cognitive function in midlife: the Coronary Artery Risk Development in Young Adults (CARDIA) study. Am J Clin Nutr. 2017;106(4):1032-1040.
Office of dietary supplements – choline [Internet]. NIH Office of Dietary Supplements. U.S. Department of Health and Human Services; [cited 2022May19]. Available from: https://ods.od.nih.gov/factsheets/Choline-HealthProfessional/   

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