Recharge NAD: Cellular Energy and Detoxification

Nicotinamide adenine dinucleotide (NAD) is key in many elements of cellular health. It acts as an energy transferring agent in cellular metabolism and is a basic requirement for almost all biological processes (1). NAD and its partner, NADH, accept and transfer electrons at critical steps in cellular energy metabolism and cycle between NAD to NADH and back again as part of the process. Beyond energy metabolism, NAD is also a key molecule in cellular communication and activates pathways linked to longevity and slowed cellular aging (1).  

Our cells can create NAD when all the necessary nutrients are available. However, the amount of NAD in our cells decreases over time, and lower levels of NAD can negatively impact our health and wellbeing. Supplementing with additional nutrients can promote more youthful cellular function.   

Every day, our cells are exposed to toxins and other damaging stressors that contribute to accelerated cellular aging. Some of these toxic stressors are byproducts of normal metabolism, while others come from environmental sources like pollution and UV rays from the sun.   

The body has powerful natural defenses to protect against toxic stressors, although sometimes these defenses struggle to keep up with the amount of exposure our cells receive. Phytonutrient compounds found in plant-based foods can further strengthen and reinforce the body’s detoxification systems and provide greater protection for cells (2-4).    

Decreased cellular energy production and exposure to toxic stressors can accelerate the effects of aging on our cells. Recharge NAD supports cellular energy with NADH and promotes cellular detoxification with potent phytonutrients, including broccoli seed extract and botanical ingredients like astragalus root to help defy aging at the cellular level.  

Designed with advanced capsule technology, Recharge NAD provides superior stability and sustained release of active ingredients. Plant-based capsules contain beadlets that are colored with natural blue spirulina extract and suspended in a blend of MCT oil and tocotrienols to both separate and protect ingredients and extend the release of nutrients.   

Broccoli seed extract: A patented and clinically studied ingredient that provides potent natural detoxification and healthy aging support. Provides the phytonutrient glucoraphanin that is metabolized into sulforaphane in the body, which increases phase II detoxification enzymes that help provide protection against oxidative and environmental stress (3,4).  

Nicotinamide adenine dinucleotide (NADH): A biologically active form of vitamin B3. In the body, NADH functions as a biological “spark plug” and operates as a strong energy provider. Its depletion may play a major role in the aging process by limiting energy production. Supplementation with NADH may help maintain adequate concentrations necessary for health and reduce symptoms of fatigue (5).  

Astragalus root: Traditionally used as an adaptogen to help increase energy and resistance to stress, astragalus has also been researched for its effects on immune health and longevity, including telomere support (6-8).  

Tocotrienols: A specialized form of vitamin E not commonly found in most foods. Tocotrienols are clinically shown to support healthy aging while being significantly more powerful for total body protection (9-11).  

Fisetin: A plant-sourced flavonoid found in fruits and vegetables such as strawberries, cucumbers, and mangoes. Fisetin is a potent supporter of cellular health.  

Facilitate your body’s natural energy production and detoxification processes with two capsules of Recharge NAD daily. Recharge NAD may be taken any time of day but is best when taken with a healthy meal. Each capsule of bright blue beadlets utilizes state-of-the-art capsule technology to deliver potent bioactives and superior stability to help you feel your best with the best nutritional technology available.  

References  

Rajman L, Chwalek K, Sinclair DA. Therapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence. Cell Metab . 2018 Mar 6;27(3):529-547.   
Kapusta-Duch J, Kopeć A, Piatkowska E, et al. The beneficial effects of Brassica vegetables on human health.  Rocz Panstw Zakl Hig . 2012;63(4):389-395.  
Riedl MA, Saxon A, Diaz-Sanchez D. Oral sulforaphane increases Phase II antioxidant enzymes in the human upper airway. Clin Immunol . 2009 Mar;130(3):244-51.   
Kensler TW, Chen JG, Egner PA, et al. Effects of glucosinolate-rich broccoli sprouts on urinary levels of aflatoxin-DNA adducts and phenanthrene tetraols in a randomized clinical trial in He Zuo township, Qidong, People’s Republic of China. Cancer Epidemiol Biomarkers Prev . 2005 Nov;14(11 Pt 1):2605-13.   
Forsyth LM, Preuss HG, MacDowell AL, et al. Therapeutic effects of oral NADH on the symptoms of patients with chronic fatigue syndrome. Ann Allergy Asthma Immunol . 1999 Feb;82(2):185-91.   
Harley CB, Liu W, Blasco M, et al. A natural product telomerase activator as part of a health maintenance program. Rejuvenation Res . 2011 Feb;14(1):45-56.   
Wang P, Zhang Z, Sun Y, et al. The two isomers of HDTIC compounds from Astragali Radix slow down telomere shortening rate via attenuating oxidative stress and increasing DNA repair ability in human fet al lung diploid fibroblast cells. DNA Cell Biol . 2010 Jan;29(1):33-9.   
Matkovic Z, Zivkovic V, Korica M, et al. Efficacy and safety of Astragalus membranaceus in the treatment of patients with seasonal allergic rhinitis. Phytother Res . 2010 Feb;24(2):175-81.   
Rasool AH, Yuen KH, Yusoff K, et al. Dose dependent elevation of plasma tocotrienol levels and its effect on arterial compliance, plasma total antioxidant status, and lipid profile in healthy humans supplemented with tocotrienol rich vitamin E. J Nutr Sci Vitaminol . 2006 Dec;52(6):473-8.   
Nor Azman NHE, Goon JA, Abdul Ghani SM, et al. Comparing Palm Oil, Tocotrienol-Rich Fraction and α-Tocopherol Supplementation on the Antioxidant Levels of Older Adults. Antioxidants. 2018 May 28;7(6):74.   
Chin SF, Hamid NA, Latiff AA, et al. Reduction of DNA damage in older healthy adults by Tri E Tocotrienol supplementation. Nutrition . 2008 Jan;24(1):1-10.  

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